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KMID : 0939920090410040233
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대한암학회지
2009 Volume.41 No. 4 p.233 ~ p.236
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A Case of Desmoplastic Small Round Cell Tumor Diagnosed in a Young Female Patient
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Kim Ji-Won
Park Jin-Hyun
Cho Hyeon-Jin
Kwon Ji-Hyun
Koh Young-Il
Kim Su-Jung
Kim Se-Hyung
Lee Se-Hoon
Im Seock-Ah
Kim Yong-Tae
Kim Woo-Ho
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Abstract
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Desmoplastic small round cell tumor is a very rare malignancy. We report the case of a 26-year-old woman who suffered from dyspepsia and abdominal pain for 2 months. We performed an endoscopic biopsy of the duodenal mass and diagnosed her disease as desmoplastic small round cell tumor using immunohistochemical staining, fluorescence in situ hybridization, and reverse transcriptase polymerase chain reaction. Because the mass invaded the pancreas and superior mesenteric vein as well as duodenum and the disease was disseminated to liver and peritoneum, she received palliative chemotherapy using vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. The maximal response to chemotherapy was stable disease. The patient expired 9 months after diagnosis.
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KEYWORD
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Desmoplastic small round cell tumor, Fluorescence in situ hybridization, Reverse transcriptase polymerase chain reaction, Chemotherapy.
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